Electron microscopic study of mouse embryonic stem cell-derived cardiomyocytes
نویسندگان
چکیده
منابع مشابه
kinetic properties of lactate dehydrogenase extraeted from mouse embryonic stem cell-derived cardiomyocytes and mouse neonatal cardiomyocytes: a comparative study
introduction: lactate dehydrogenase is one of the cardiac enzyme markers, studied in vivo. in the present study, activity and kinetic properties of enzyme extracted from cardiomycytes derived from mouse embyronic stem cell in vitro were compared with enzyme extracted mouse neonatal from cardiomyocytes in vivo. material and methods: mouse embryonic stem cells were cultured and differentiated and...
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introduction: stem cell biology has been the subject of much recent discussion. embryonic stem (es) cells, derived from the inner cell mass of the blastocyst stage of early mammalian embryos are expected to become a powerful tool in future regenerative medicine and developmental biology due to their capacity of self-renewal and pluripotency. in the present study, the ultrastructural development...
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Purpose: We investigated the effect of (bFGF) (basic-Fibroblast Growth Factor) on the differentiation of divided cardiomyocytes from mouse embryonic stem cells (ES) and their pharmacological properties. Materials and Methods: The mouse embryonic stem cells (Royan B1) were cultured as 800 cells per 20µl of a hanging drop. After two days, ES cells in each drop aggregated to form embryoid bodies ...
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Background DOX is a powerful chemotherapeutic agent used in the treatment of solid tumors and malignant hematological diseases. However, its cardiac toxicity limits the clinical usefulness of this drug. Previous reports have shown Corticosteroids induce a cytoprotective effect on cardiomyocytes. Mouse transgenic embryonic stem cell-derived pure cardiomyocytes may be considered as a model for a...
متن کاملCa2+ removal mechanisms in mouse embryonic stem cell-derived cardiomyocytes.
In mammalian adult cardiomyocytes, sarcoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA) plays a major role in controlling the decline of cytosolic free Ca(2+) concentration ([Ca(2+)](i)) in comparison with sarcolemmal Na(+)/Ca(2+) exchanger (NCX). However, the functional importance of SERCA and NCX in cytosolic Ca(2+) removal during early cardiomyogenesis is still debated. In this study, the funct...
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ژورنال
عنوان ژورنال: Cytotechnology
سال: 2011
ISSN: 0920-9069,1573-0778
DOI: 10.1007/s10616-011-9411-4